Mr Zuckerberg, 37, appeared to challenge claims made by Ms Haugen, 39, as he shared a note he wrote to Facebook’s company employees to the social media platform.
In his 1324-word post, the Facebook founder said: “We care deeply about issues like safety, well-being and mental health.
“It’s difficult to see coverage that misrepresents our work and our motives.
“At the most basic level, I think most of us just don’t recognize the false picture of the company that is being painted.”
He added: “Many of the claims don’t make any sense.”
Mr Zuckerberg’s post has come after a difficult week for the social media giant.
Facebook, WhatsApp and Instagram suffered from a major network outage on Monday which left users locked out of their social media accounts for up to seven-hours.
But Facebook was also hit by allegations by Ms Haugen that the company chases profit over ensuring the safety of the network’s users.
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