The Police force are appealing for information and confirmed an investigation is “underway”. The man, in his 20s, was sadly pronounced dead at the scene and his next of kin have been informed.
The injured man, also in his 20s was airlifted to hospital where he is being treated for leg injuries.
Detective Chief Inspector Wes Knights, of GMP’s Major Incident Team, said: “I send our condolences to the loved ones of the man who’s sadly died and our well wishes to the man who’s receiving treatment in hospital.
“Specially trained officers will be deployed to support them.
“We are in the early stages of our investigation but we are carrying out extensive enquiries to establish the full circumstances surrounding this incident.
“Members of the public should expect to see extra officers in Ancoats over the coming days.
“Whilst officers are gathering evidence from the scene and the surrounding area, I would like to use this opportunity to appeal to anyone with information to share it with us – this can also be done anonymously via Crimestoppers.
“I also ask anyone who has dash cam footage from Ancoats this evening to contact us.”